Malignant Pleural Effusions: Mistletoe Spray Instead of Talc Poudrage?

Thoracoscopic talc poudrage in malignant pleural effusions: effective pleurodesis despite low pleural pH.

STUDY OBJECTIVE To determine the effectiveness of pleurodesis by thoracoscopic talc poudrage (TTP) in patients with low pH malignant pleural effusions. DESIGN Review of prospectively collected data on all thoracoscopic procedures performed from 1982 to 1996. PATIENTS AND SETTING Twenty-five members in a prepaid, closed-panel health maintenance organization, whose malignant pleural effusion ...

Talc pleurodesis for treating malignant pleural effusions.

Malignant pleural effusions and the role of talc poudrage and talc slurry: a systematic review and meta-analysis

BACKGROUND Malignant Pleural Effusion (MPE) is common with advanced malignancy. Palliative care with minimal adverse events is the cornerstone of management. Although talc pleurodesis plays an important role in treatment, the best modality of talc application remains controversial.   OBJECTIVE To compare recurrence rates, rates of respiratory and non-respiratory complications between thoracos...

Phase III intergroup study of talc poudrage vs talc slurry sclerosis for malignant pleural effusion.

STUDY OBJECTIVE To demonstrate the efficacy, safety, and appropriate mode of instillation of talc for sclerosis in treatment of malignant pleural effusions (MPEs). DESIGN A prospective, randomized trial was designed to compare thoracoscopy with talc insufflation (TTI) to thoracostomy and talc slurry (TS) for patients with documented MPE. MEASUREMENTS The primary end point was 30-day freedom...

Talc: Rationale and Use in Malignant Pleural Effusions.

Neoplastic diseases account for approximately 13% of the annual incidence of pleural effusions, and 75% of these effusions are secondary to malignancies of the lungs and breast or lymphoma. The most common pathogenic mechanisms that produce malignant pleural effusions (MPE) are (1) pleural metastasis resulting in increased membrane permeability beyond the capacity of lymphatic drainage, (2) met...